How the coronavirus enter human cells 新型冠狀病毒是如何進入人體細胞的?



The large S-Glycoproteins are used by the virus to gain entry to human cells. They』re most likely to attach angiotensin converting enzyme 2 receptors on the cell and let them allow the virus entry. The exact mechanism for this is not known, mostly likely, as shown here, the human cell ingests the virus in a process known as 「Endocytosis」. Once inside the cytoplasm, the endosome opens to reveal the virus』s genetic material, a single stranded RNA. The virus hijacks the cell』s machinery to replicate the RNA in N-proteins and uses the endoplasmic reticulum to form its M-protein outer layer and the all important S-protein. After the replication a virus is carried by the Golgi bodies out of the cell in the process, known as Exocytosis, so that it can infect other cells. Meanwhile the stressor viral production at the end of plasmid reticulum eventually leads to apoptosis or cell death.

病毒使用大的S-糖蛋白進入人體細胞。它們最有可能附著在細胞的血管緊張素轉換酶2受體上使它們允許病毒進入細胞。確切的機理尚不清楚,但多數情況中如下所示。人體細胞以被稱為「胞吞作用」的過程攝入病毒。一旦進入細胞質,內體就會打開並顯示病毒的遺傳物質,即單鏈RNA。該病毒如同「劫持」了細胞的某種機制,使其複製N蛋白中的RNA,並利用內質網形成其M蛋白螺旋層和對此螺旋層重要的S蛋白。複製完成後,高爾基體會攜帶病毒至細胞外,這個過程被稱為「胞吐作用」,之後它可以感染其他細胞。同時,在質粒網狀結構末端的應激病毒產物最終導致細胞凋亡或細胞死亡。 .

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