How the coronavirus enter human cells 新型冠状病毒是如何进入人体细胞的？

The large S-Glycoproteins are used by the virus to gain entry to human cells. They’re most likely to attach angiotensin converting enzyme 2 receptors on the cell and let them allow the virus entry. The exact mechanism for this is not known, mostly likely, as shown here, the human cell ingests the virus in a process known as “Endocytosis”. Once inside the cytoplasm, the endosome opens to reveal the virus’s genetic material, a single stranded RNA. The virus hijacks the cell’s machinery to replicate the RNA in N-proteins and uses the endoplasmic reticulum to form its M-protein outer layer and the all important S-protein. After the replication a virus is carried by the Golgi bodies out of the cell in the process, known as Exocytosis, so that it can infect other cells. Meanwhile the stressor viral production at the end of plasmid reticulum eventually leads to apoptosis or cell death.

病毒使用大的S-糖蛋白进入人体细胞。它们最有可能附着在细胞的血管紧张素转换酶2受体上使它们允许病毒进入细胞。确切的机理尚不清楚，但多数情况中如下所示。人体细胞以被称为“胞吞作用”的过程摄入病毒。一旦进入细胞质，内体就会打开并显示病毒的遗传物质，即单链RNA。该病毒如同“劫持”了细胞的某种机制，使其复制N蛋白中的RNA，并利用内质网形成其M蛋白螺旋层和对此螺旋层重要的S蛋白。复制完成后，高尔基体会携带病毒至细胞外，这个过程被称为“胞吐作用”，之后它可以感染其他细胞。同时，在质粒网状结构末端的应激病毒产物最终导致细胞凋亡或细胞死亡。 .